When trying to install Sametime 7.5 Server on a computer running Sophos Antivirus be sure to disable the antivirus service while installing. If you don’t you’ll most likely get an error saying “Installation has detected some Domino or Sametime processes already running” and you will be unable to continue. The answer was found in technote 1245237.
Technote 1245237:
Error installing Sametime 7.5 server: ‘Installation has detected some Domino or Sametime processes’…
lekkimworld.com 
Have encountered this same problem with the computer associates antivirus a while ago….. sure had me scratching my head for a while
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Yeah – shutting down the anti virus isn’t the first thing you think of with an error message like that… 😉
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